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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 5,340 Icelandic ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.198 lower (95% confidence interval 0.14-0.26); p = 1 × 10−11.
How common The G allele had a frequency of about 10% in the people studied.
Where it sits Chromosome 15, band 15q25.1 — in an intron of CTSH.
What each result means
A/ANo copy of the version the research linked to Serum levels of protein CTSH. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Serum levels of protein CTSH. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Serum levels of protein CTSH. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2022 · PMID 35078996 · open access
Questions about rs8034542
What is rs8034542?
rs8034542 is a single position in the genome, in or near the CTSH gene. Published research associates it with serum levels of protein ctsh. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs8034542 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs8034542 come from?
GWAS Catalog, Nature communications 2022, PMID:35078996. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Serum levels of protein CTSH (rs8034542). MyGeneLog™. https://www.mygenelog.com/variants/rs8034542