Sensitive

Surgical hip osteoarthritis

BMP5 · rs80287694

Where this position leads

Condition: Hip Osteoarthritis

rs80287694 Condition: Hip Osteoarthritis Hip Osteoarthritis Condition rs80287694 rs80287694 BMP5

What the study found

Who was studied 20,221 European ancestry cases, 626,610 European ancestry controls.

The effect Each copy of the G allele carried 1.12 times the odds of Surgical hip osteoarthritis (95% confidence interval 1.08-1.16); p = 6 × 10−11.

How common The G allele had a frequency of about 10% in the people studied.

Where it sits Chromosome 6, band 6p12.1 — in an intron of BMP5.

What each result means

A/A No copy of the version the research linked to Surgical hip osteoarthritis. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Surgical hip osteoarthritis. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Surgical hip osteoarthritis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs80287694

What is rs80287694?

rs80287694 is a single position in the genome, in or near the BMP5 gene. Published research associates it with surgical hip osteoarthritis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs80287694 linked to?

On MyGeneLog this position is linked to Hip Osteoarthritis. The research behind each link, and its sources, are set out on that condition page.

Does having rs80287694 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs80287694 come from?

GWAS Catalog, Annals of the rheumatic diseases 2023, PMID:36376028. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Surgical hip osteoarthritis (rs80287694). MyGeneLog™. https://www.mygenelog.com/variants/rs80287694

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