Standard

Estimated glomerular filtration rate

WDR37 · rs80282103

Where this position leads

Condition: Kidney Function

rs80282103 Condition: Kidney Function Kidney Function Condition rs80282103 rs80282103 WDR37

What the study found

Who was studied 134,070 European ancestry individuals, 143,658 East Asian ancestry individuals, 26,344 Hispanic or Latino ancestry individuals, 8,224 African American individuals.

The effect Each copy of the T allele shifted the measure 0.615 ml/min/1.73m2 lower (95% confidence interval 0.31-0.92); p = 2 × 10−18.

How common The T allele had a frequency of about 8% in the people studied.

Where it sits Chromosome 10, band 10p15.3 — in an intron of LARP4B.

What each result means

A/A No copy of the version the research linked to Estimated glomerular filtration rate. This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Estimated glomerular filtration rate. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Estimated glomerular filtration rate. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs80282103

What is rs80282103?

rs80282103 is a single position in the genome, in or near the WDR37 gene. Published research associates it with estimated glomerular filtration rate. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs80282103 linked to?

On MyGeneLog this position is linked to Kidney Function. The research behind each link, and its sources, are set out on that condition page.

Does having rs80282103 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs80282103 come from?

GWAS Catalog, Nat Commun 2019, PMID:30604766. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Estimated glomerular filtration rate (rs80282103). MyGeneLog™. https://www.mygenelog.com/variants/rs80282103

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