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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 3,146 European ancestry individuals.
The effect
The reported allele is A; the catalogue records no effect size
; p = 5 × 10−9.
How common The A allele had a frequency of about 20% in the people studied.
Where it sits Chromosome 15, band 15q11.2 — in an intron of PWRN1.
What each result means
A/ATwo copies of the version the research linked to Cerebrospinal fluid t-tau:AB1-42 ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Cerebrospinal fluid t-tau:AB1-42 ratio. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Cerebrospinal fluid t-tau:AB1-42 ratio. This is the starting point the study compared everyone against.
Alzheimer's research & therapy · 2018 · PMID 30153862 · open access
Questions about rs8027714
What is rs8027714?
rs8027714 is a single position in the genome, in or near the C15orf2 gene. Published research associates it with cerebrospinal fluid t-tau:ab1-42 ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs8027714 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs8027714 come from?
GWAS Catalog, Alzheimers Res Ther 2018, PMID:30153862. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Cerebrospinal fluid t-tau:AB1-42 ratio (rs8027714). MyGeneLog™. https://www.mygenelog.com/variants/rs8027714