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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 33,907 European or unknown ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0426 lower (95% confidence interval 0.03-0.055); p = 2 × 10−11.
How common The G allele had a frequency of about 64% in the people studied.
Where it sits Chromosome 14, band 14q32.12 — in an intron of FBLN5.
What each result means
A/ANo copy of the version the research linked to Descending aorta distensibility. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Descending aorta distensibility. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Descending aorta distensibility. That is the strongest link of the three results. A link in a study is not a diagnosis.
Journal of the American College of Cardiology · 2023 · PMID 37019578
Questions about rs8023114
What is rs8023114?
rs8023114 is a single position in the genome, in or near the FBLN5 gene. Published research associates it with descending aorta distensibility. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs8023114 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs8023114 come from?
GWAS Catalog, Journal of the American College of Cardiology 2023, PMID:37019578. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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