Standard

Mean corpuscular volume

SPIDR · rs80226431

What the study found

Who was studied 362,595 British ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.16 % higher (95% confidence interval 0.12-0.2); p = 2 × 10−17.

How common The A allele had a frequency of about 90% in the people studied.

Where it sits Chromosome 8, band 8q11.21 — in an intron of SPIDR.

What each result means

A/A Two copies of the version the research linked to Mean corpuscular volume. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Mean corpuscular volume. That is a smaller link than two copies.
T/T No copy of the version the research linked to Mean corpuscular volume. This is the starting point the study compared everyone against.
Source

Questions about rs80226431

What is rs80226431?

rs80226431 is a single position in the genome, in or near the SPIDR gene. Published research associates it with mean corpuscular volume. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs80226431 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs80226431 come from?

GWAS Catalog, Human molecular genetics 2021, PMID:34104963. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Mean corpuscular volume (rs80226431). MyGeneLog™. https://www.mygenelog.com/variants/rs80226431

← See all variants