0 1014212Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI4Microsoft · Copilot0Amazon2Apple1China (ByteDance, Huawei, Baidu…)0Others2Total10Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 628 European ancestry cases, 7,352 European ancestry controls.
The effect
Each copy of the G allele carried 1.68 times the odds of Classic bladder exstrophy (95% confidence interval 1.47-1.92); p = 2 × 10−14.
Where it sits Chromosome 3, band 3q22.3 — between genes, 48.7 kb from HSPA8P9.
What each result means
A/ANo copy of the version the research linked to Classic bladder exstrophy. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Classic bladder exstrophy. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Classic bladder exstrophy. That is the strongest link of the three results. A link in a study is not a diagnosis.
Communications biology · 2022 · PMID 36352089 · open access
Questions about rs80215221
What is rs80215221?
rs80215221 is a single position in the genome, in or near the near HSPA8P9 gene. Published research associates it with classic bladder exstrophy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs80215221 linked to?
On MyGeneLog this position is linked to Classic Bladder Exstrophy. The research behind each link, and its sources, are set out on that condition page.
Does having rs80215221 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs80215221 come from?
GWAS Catalog, Communications biology 2022, PMID:36352089. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1014212Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI4Microsoft · Copilot0Amazon2Apple1China (ByteDance, Huawei, Baidu…)0Others2Total10Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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