2 444216223222Reads by AI crawlersClaude4ChatGPT2Google · Gemini0Perplexity1Meta AI6Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others22Total44Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 1,840 European ancestry cases, 5,163 European ancestry controls and (Liu et al); replicated in 620 European ancestry cases, 2,514 European ancestry controls.
The effect
Each copy of the A allele carried 1.22 times the odds of Primary biliary cholangitis (95% confidence interval 1.16-1.27); p = 3 × 10−13.
How common The A allele had a frequency of about 40% in the people studied.
Where it sits Chromosome 14, band 14q32.32 — in an intron of EXOC3L4.
What each result means
A/ATwo copies of the version the research linked to Primary biliary cholangitis. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Primary biliary cholangitis. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Primary biliary cholangitis. This is the starting point the study compared everyone against.
Nature genetics · 2011 · PMID 21399635 · open access
Questions about rs8017161
What is rs8017161?
rs8017161 is a single position in the genome, in or near the TNFAIP2 gene. Published research associates it with primary biliary cholangitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs8017161 linked to?
On MyGeneLog this position is linked to Primary Biliary Cholangitis. The research behind each link, and its sources, are set out on that condition page.
Does having rs8017161 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs8017161 come from?
GWAS Catalog, Nat Genet 2011, PMID:21399635. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 444216223222Reads by AI crawlersClaude4ChatGPT2Google · Gemini0Perplexity1Meta AI6Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others22Total44Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.