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Sensitivity to environmental stress and adversity

LINC02210-CRHR1 · rs80143279

What the study found

Who was studied 351,827 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0268 higher; p = 8 × 10−22.

Where it sits Chromosome 17, band 17q21.31 — in an intron of LINC02210-CRHR1.

What each result means

C/C Two copies of the version the research linked to Sensitivity to environmental stress and adversity. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Sensitivity to environmental stress and adversity. That is a smaller link than two copies.
T/T No copy of the version the research linked to Sensitivity to environmental stress and adversity. This is the starting point the study compared everyone against.
Source

Questions about rs80143279

What is rs80143279?

rs80143279 is a single position in the genome, in or near the LINC02210-CRHR1 gene. Published research associates it with sensitivity to environmental stress and adversity. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs80143279 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs80143279 come from?

GWAS Catalog, Acta psychiatrica Scandinavica 2020, PMID:31972866. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Sensitivity to environmental stress and adversity (rs80143279). MyGeneLog™. https://www.mygenelog.com/variants/rs80143279

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