Sensitive

Chronic obstructive pulmonary disease liability (machine learning-based score)

RAD51B · rs8014234

What the study found

Who was studied 325,027 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0136 higher (95% confidence interval 0.0095-0.0177); p = 1 × 10−11.

Where it sits Chromosome 14, band 14q24.1 — in an intron of RAD51B.

What each result means

A/A Two copies of the version the research linked to Chronic obstructive pulmonary disease liability (machine learning-based score). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Chronic obstructive pulmonary disease liability (machine learning-based score). That is a smaller link than two copies.
G/G No copy of the version the research linked to Chronic obstructive pulmonary disease liability (machine learning-based score). This is the starting point the study compared everyone against.
Source

Questions about rs8014234

What is rs8014234?

rs8014234 is a single position in the genome, in or near the RAD51B gene. Published research associates it with chronic obstructive pulmonary disease liability (machine learning-based score). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs8014234 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs8014234 come from?

GWAS Catalog, Nature genetics 2023, PMID:37069358. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Chronic obstructive pulmonary disease liability (machine learning-based score) (rs8014234). MyGeneLog™. https://www.mygenelog.com/variants/rs8014234

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