Standard

Height

REM2 · rs8014119

Where this position leads

Condition: Height

rs8014119 Condition: Height Height Condition rs8014119 rs8014119 REM2

What the study found

Who was studied 5,314,291 European ancestry, Hispanic or Latin American, East Asian ancestry, African ancestry, South Asian ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.007 higher (95% confidence interval 0.0048-0.0092); p = 6 × 10−10.

How common The C allele had a frequency of about 9% in the people studied.

Where it sits Chromosome 14, band 14q11.2 — a missense change in REM2.

What ClinVar records

Classification Benign; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 2 submitters), last evaluated 2018-07-13. ClinVar record 1231760 NM_173527.3(REM2):c.287G>C (p.Gly96Ala)

What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.

What each result means

C/C Two copies of the version the research linked to Height. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Height. That is a smaller link than two copies.
G/G No copy of the version the research linked to Height. This is the starting point the study compared everyone against.
Source

Questions about rs8014119

What is rs8014119?

rs8014119 is a single position in the genome, in or near the REM2 gene. Published research associates it with height. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs8014119 linked to?

On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.

Does having rs8014119 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs8014119 come from?

GWAS Catalog, Nature 2022, PMID:36224396. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Height (rs8014119). MyGeneLog™. https://www.mygenelog.com/variants/rs8014119

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