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Lung function (FEV1) and body mass index

near VTRNA1-3 · rs801170

What the study found

Who was studied up to 100,285 Chinese ancestry individuals; replicated in up to 457,756 European ancestry individuals.

The effect The reported allele is C; the catalogue records no effect size ; p = 9 × 10−13.

Where it sits Chromosome 5, band 5q31.3 — between genes, 9.5 kb from VTRNA1-3.

What each result means

C/C Two copies of the version the research linked to Lung function (FEV1) and body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Lung function (FEV1) and body mass index. That is a smaller link than two copies.
T/T No copy of the version the research linked to Lung function (FEV1) and body mass index. This is the starting point the study compared everyone against.
Source

Questions about rs801170

What is rs801170?

rs801170 is a single position in the genome, in or near the near VTRNA1-3 gene. Published research associates it with lung function (fev1) and body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs801170 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs801170 come from?

GWAS Catalog, The European respiratory journal 2021, PMID:33766948. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Lung function (FEV1) and body mass index (rs801170). MyGeneLog™. https://www.mygenelog.com/variants/rs801170

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