Standard

HDL cholesterol levels

near MIR138-2 · rs80072323

What the study found

Who was studied 38,000 South Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.072 lower (95% confidence interval 0.05-0.094); p = 1 × 10−11.

Where it sits Chromosome 16, band 16q13 — between genes, 0.3 kb from MIR138-2.

What each result means

A/A Two copies of the version the research linked to HDL cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to HDL cholesterol levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to HDL cholesterol levels. This is the starting point the study compared everyone against.
Source

Questions about rs80072323

What is rs80072323?

rs80072323 is a single position in the genome, in or near the near MIR138-2 gene. Published research associates it with hdl cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs80072323 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs80072323 come from?

GWAS Catalog, Nature communications 2024, PMID:39414775. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

HDL cholesterol levels (rs80072323). MyGeneLog™. https://www.mygenelog.com/variants/rs80072323

← See all variants