near N4BP2L2 · rs7998440
Where this position leads
Condition: Coronary Artery Disease
What the study found
Who was studied up to 122,733 cases, up to 424,528 controls.
The effect Each copy of the A allele shifted the measure 0.0383 lower (95% confidence interval 0.027-0.05); p = 1 × 10−10.
How common The A allele had a frequency of about 35% in the people studied.
Where it sits Chromosome 13, band 13q13.1 — between genes, 12.2 kb from N4BP2L2.
rs7998440 is a single position in the genome, in or near the near N4BP2L2 gene. Published research associates it with coronary artery disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Coronary Artery Disease. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Circ Res 2017, PMID:29212778. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Coronary artery disease (rs7998440). MyGeneLog™. https://www.mygenelog.com/variants/rs7998440