Sensitive

Nonalcoholic fatty liver disease (without comorbidities)

CLDN10 · rs7996045

Where this position leads

Condition: Nonalcoholic Fatty Liver Disease (NAFLD)

rs7996045 Condition: Nonalcoholic Fatty Liver Disease (NAFLD) Nonalcoholic Fatty Liver Disease (NAFLD) Condition rs7996045 rs7996045 CLDN10

What the study found

Who was studied 424 Korean ancestry cases, 5,402 Korean ancestry controls.

The effect Each copy of the T allele carried 2.67 times the odds of Nonalcoholic fatty liver disease (without comorbidities) (95% confidence interval 1.9-3.81); p = 2 × 10−8.

Where it sits Chromosome 13, band 13q32.1 — in an intron of CLDN10.

What each result means

A/A No copy of the version the research linked to Nonalcoholic fatty liver disease (without comorbidities). This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Nonalcoholic fatty liver disease (without comorbidities). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Nonalcoholic fatty liver disease (without comorbidities). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7996045

What is rs7996045?

rs7996045 is a single position in the genome, in or near the CLDN10 gene. Published research associates it with nonalcoholic fatty liver disease (without comorbidities). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7996045 linked to?

On MyGeneLog this position is linked to Nonalcoholic Fatty Liver Disease (NAFLD). The research behind each link, and its sources, are set out on that condition page.

Does having rs7996045 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7996045 come from?

GWAS Catalog, GWAS Catalog n.d., PMID:37133724. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Nonalcoholic fatty liver disease (without comorbidities) (rs7996045). MyGeneLog™. https://www.mygenelog.com/variants/rs7996045

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