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Acute myeloid leukemia (complex karyotype)

EPCAM-DT · rs79918355

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 358 European ancestry cases, 12,938 European ancestry controls.

The effect Each copy of the A allele carried 2.80 times the odds of Acute myeloid leukemia (complex karyotype) (95% confidence interval 2.0-3.91); p = 2 × 10⁻⁹.

How common The A allele had a frequency of about 3% in the people studied.

Where it sits Chromosome 2, band 2p21 — in an intron of EPCAM-DT.

What each result means

A/A Two copies of the version the research linked to Acute myeloid leukemia (complex karyotype). That is the strongest link of the three results. A link in a study is not a diagnosis.

A/G One copy of the version the research linked to Acute myeloid leukemia (complex karyotype). That is a smaller link than two copies.

G/G No copy of the version the research linked to Acute myeloid leukemia (complex karyotype). This is the starting point the study compared everyone against.

Source

Common variation at 1q23.3, 2p23.3, 2q33.3, and 2p21 influences the risk of acute myeloid leukemia

Ranasinghe D, Lin WY, Fordham SE, Alharbi A, Sunter NJ, Elstob C, Nahari MH, Xu Y, Park C, Hungate E, Quante A, Strauch K

and 82 more — show all

Gieger C, Skol A, Rahman T, Sucheston-Campbell L, Hahn T, Clay-Gilmour AI, Jones GL, Marr HJ, Jackson GH, Menne T, Collin M, Ivey A, Hills RK, Burnett AK, Russell NH, Fitzgibbon J, Larson RA, Le Beau MM, Stock W, Heidenreich O, Enshaei A, Gunasinghe D, Hawking ZL, Heslop H, Nandana D, Di B, Plokhuta A, Brown IT, Allsup DJ, Houlston RS, Collins A, Milne P, Norden J, Dickinson AM, Lendrem C, Daly AK, Palm L, Piechocki K, Jeffries S, Bornhäuser M, Röllig C, Altmann H, Ruhnke L, Kunadt D, Wagenführ L, Cordell HJ, Darlay R, Andersen MK, Fontana MC, Martinelli G, Marconi G, Sanz MA, Cervera J, Gómez-Seguí I, Cluzeau T, Moreilhon C, Raynaud S, Sill H, Voso MT, Dombret H, Cheok M, Preudhomme C, Gale RE, Linch D, Weisinger J, Masszi A, Nowak D, Hofmann WK, Gilkes A, Porkka K, Milosevic Feenstra JD, Kralovics R, Wang J, Meggendorfer M, Haferlach T, Krizsán S, Bödör C, Parkin B, Malek SN, Stölzel F, Onel K, Allan JM

Blood · 2026 · PMID 41610418

Questions about rs79918355

What is rs79918355?

rs79918355 is a single position in the genome, in or near the EPCAM-DT gene. Published research associates it with acute myeloid leukemia (complex karyotype). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs79918355 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs79918355 come from?

GWAS Catalog, Blood 2026, PMID:41610418. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Acute myeloid leukemia (complex karyotype) (rs79918355). MyGeneLog™. https://www.mygenelog.com/variants/rs79918355

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