Standard
Monocyte percentage of white cells
near CDC5L · rs79894332
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 408,112 British individuals.
The effect
Each copy of the A allele shifted the measure 0.044 lower (95% confidence interval 0.037-0.051); p = 6 × 10−33.
How common The A allele had a frequency of about 10% in the people studied.
Where it sits Chromosome 6, band 6p21.1 — between genes, 173.6 kb from CDC5L.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Monocyte percentage of white cells compared to the general population.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Monocyte percentage of white cells.
G/G
Published research associates this genotype with typical/baseline likelihood of Monocyte percentage of white cells — no copies of the reported risk allele.
Source
The Polygenic and Monogenic Basis of Blood Traits and Diseases
Vuckovic D,
Bao EL,
Akbari P,
Lareau CA,
Mousas A,
Jiang T,
Chen MH,
Raffield LM,
Tardaguila M,
Huffman JE,
Ritchie SC,
Megy K
and 100 more — show all
Ponstingl H,
Penkett CJ,
Albers PK,
Wigdor EM,
Sakaue S,
Moscati A,
Manansala R,
Lo KS,
Qian H,
Akiyama M,
Bartz TM,
Ben-Shlomo Y,
Beswick A,
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Bottinger EP,
Brody JA,
van Rooij FJA,
Chitrala KN,
Wilson PWF,
Choquet H,
Danesh J,
Di Angelantonio E,
Dimou N,
Ding J,
Elliott P,
Esko T,
Evans MK,
Felix SB,
Floyd JS,
Broer L,
Grarup N,
Guo MH,
Guo Q,
Greinacher A,
Haessler J,
Hansen T,
Howson JMM,
Huang W,
Jorgenson E,
Kacprowski T,
Kähönen M,
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Kanai M,
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Koskeridis F,
Lange LA,
Lehtimäki T,
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Liu Y,
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Manichaikul A,
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Mononen N,
Murakami Y,
Nadkarni GN,
Nikus K,
Pankratz N,
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Preuss M,
Psaty BM,
Raitakari OT,
Rich SS,
Rodriguez BAT,
Rosen JD,
Rotter JI,
Schubert P,
Spracklen CN,
Surendran P,
Tang H,
Tardif JC,
Ghanbari M,
Völker U,
Völzke H,
Watkins NA,
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Cai N,
Kundu K,
Watt SB,
Walter K,
Zonderman AB,
Cho K,
Li Y,
Loos RJF,
Knight JC,
Georges M,
Stegle O,
Evangelou E,
Okada Y,
Roberts DJ,
Inouye M,
Johnson AD,
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Reiner AP,
Butterworth AS,
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Lettre G,
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Soranzo N
Cell · 2020 · PMID 32888494 · open access
Questions about rs79894332
What is rs79894332?
rs79894332 is a single position in the genome, in or near the near CDC5L gene. Published research associates it with monocyte percentage of white cells. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs79894332 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs79894332 come from?
GWAS Catalog, Cell 2020, PMID:32888494. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Monocyte percentage of white cells (rs79894332). MyGeneLog™. https://www.mygenelog.com/variants/rs79894332
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