Standard
Bone mineral density (paediatric, upper limb)
FAM3C · rs798943
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype with typical/baseline likelihood of Bone mineral density (paediatric, upper limb) — no copies of the reported risk allele. (GWAS Catalog, PLoS Genet 2014, PMID:24945404)
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Bone mineral density (paediatric, upper limb). (GWAS Catalog, PLoS Genet 2014, PMID:24945404)
G/G
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Bone mineral density (paediatric, upper limb) compared to the general population. (GWAS Catalog, PLoS Genet 2014, PMID:24945404)
Source
Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment
Kemp JP,
Medina-Gomez C,
Estrada K,
St Pourcain B,
Heppe DH,
Warrington NM,
Oei L,
Ring SM,
Kruithof CJ,
Timpson NJ,
Wolber LE,
Reppe S
and 21 more — show all
Gautvik K,
Grundberg E,
Ge B,
van der Eerden B,
van de Peppel J,
Hibbs MA,
Ackert-Bicknell CL,
Choi K,
Koller DL,
Econs MJ,
Williams FM,
Foroud T,
Zillikens MC,
Ohlsson C,
Hofman A,
Uitterlinden AG,
Davey Smith G,
Jaddoe VW,
Tobias JH,
Rivadeneira F,
Evans DM
PLoS genetics · 2014 · PMID 24945404 · open access
Questions about rs798943
What is rs798943?
rs798943 is a single position in the genome, in or near the FAM3C gene. Published research associates it with bone mineral density (paediatric, upper limb). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs798943 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs798943 come from?
GWAS Catalog, PLoS Genet 2014, PMID:24945404. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants