Standard

Medication use (calcium channel blockers)

RXFP2 · rs7983337

Where this position leads

Condition: Medication Use as a Genetic Trait

rs7983337 Condition: Medication Use as a Genetic Trait Medication Use as a Genetic Trait Condition rs7983337 rs7983337 RXFP2

What the study found

Who was studied 31,904 European ancestry cases, 172,474 European ancestry controls.

The effect Each copy of the C allele shifted the measure 0.0773 lower (95% confidence interval 0.061-0.093); p = 1 × 10−21.

How common The C allele had a frequency of about 49% in the people studied.

Where it sits Chromosome 13, band 13q13.1 — between genes, 132.1 kb from RXFP2.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Medication use (calcium channel blockers) compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Medication use (calcium channel blockers).
T/T Published research associates this genotype with typical/baseline likelihood of Medication use (calcium channel blockers) — no copies of the reported risk allele.
Source

Questions about rs7983337

What is rs7983337?

rs7983337 is a single position in the genome, in or near the RXFP2 gene. Published research associates it with medication use (calcium channel blockers). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7983337 linked to?

On MyGeneLog this position is linked to Medication Use as a Genetic Trait. The research behind each link, and its sources, are set out on that condition page.

Does having rs7983337 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7983337 come from?

GWAS Catalog, Nat Commun 2019, PMID:31015401. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Medication use (calcium channel blockers) (rs7983337). MyGeneLog™. https://www.mygenelog.com/variants/rs7983337

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