Who was studied 342,286 European ancestry individuals, 6,015 African ancestry individuals, 7,336 South Asian ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.118 lower (95% confidence interval 0.099-0.138); p = 1 × 10−32.
Where it sits Chromosome 5, band 5p13.1 — inside TTC33.
What each result means
C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Urea levels compared to the general population.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Urea levels.
T/TPublished research associates this genotype with typical/baseline likelihood of Urea levels — no copies of the reported risk allele.
Nature genetics · 2021 · PMID 33462484 · open access
Questions about rs79831708
What is rs79831708?
rs79831708 is a single position in the genome, in or near the TTC33 gene. Published research associates it with urea levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs79831708 linked to?
On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.
Does having rs79831708 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs79831708 come from?
GWAS Catalog, Nat Genet 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.