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Apolipoprotein A1 levels

near GPIHBP1 · rs79744701

What the study found

Who was studied 311,601 European ancestry individuals, 5,550 African ancestry individuals, 6,682 South Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0382 higher (95% confidence interval 0.031-0.046); p = 8 × 10−24.

Where it sits Chromosome 8, band 8q24.3 — between genes, 6.3 kb from GPIHBP1.

What each result means

A/A Two copies of the version the research linked to Apolipoprotein A1 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Apolipoprotein A1 levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Apolipoprotein A1 levels. This is the starting point the study compared everyone against.
Source

Questions about rs79744701

What is rs79744701?

rs79744701 is a single position in the genome, in or near the near GPIHBP1 gene. Published research associates it with apolipoprotein a1 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs79744701 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs79744701 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Apolipoprotein A1 levels (rs79744701). MyGeneLog™. https://www.mygenelog.com/variants/rs79744701

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