Sensitive

Attention deficit hyperactivity disorder or cannabis use

POC1B · rs797267

Where this position leads

Condition: ADHD (Attention Deficit Hyperactivity Disorder)

rs797267 Condition: ADHD (Attention Deficit Hyperactivity Disorder) ADHD (Attention Deficit Hyperactivi… Condition rs797267 rs797267 POC1B

What the study found

Who was studied 18,345 European ancestry ADHD cases, 14,374 European ancestry cannabis use cases, 50,410 European ancestry controls.

The effect Each copy of the G allele carried 1.10 times the odds of Attention deficit hyperactivity disorder or cannabis use (95% confidence interval 1.06-1.12); p = 4 × 10−9.

Where it sits Chromosome 12, band 12q21.33 — between genes, 21 kb from DUSP6.

What each result means

A/A No copy of the version the research linked to Attention deficit hyperactivity disorder or cannabis use. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Attention deficit hyperactivity disorder or cannabis use. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Attention deficit hyperactivity disorder or cannabis use. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs797267

What is rs797267?

rs797267 is a single position in the genome, in or near the POC1B gene. Published research associates it with attention deficit hyperactivity disorder or cannabis use. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs797267 linked to?

On MyGeneLog this position is linked to ADHD (Attention Deficit Hyperactivity Disorder). The research behind each link, and its sources, are set out on that condition page.

Does having rs797267 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs797267 come from?

GWAS Catalog, Mol Psychiatry 2019, PMID:30610198. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Attention deficit hyperactivity disorder or cannabis use (rs797267). MyGeneLog™. https://www.mygenelog.com/variants/rs797267

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