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High-sensitivity C-reactive protein levels

CABP1 · rs7965649

Where this position leads

Condition: C-Reactive Protein Levels

rs7965649 Condition: C-Reactive Protein Levels C-Reactive Protein Levels Condition rs7965649 rs7965649 CABP1

What the study found

Who was studied 71,019 Korean ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.055 lower (95% confidence interval 0.036-0.074); p = 1 × 10−8.

How common The T allele had a frequency of about 6% in the people studied.

Where it sits Chromosome 12, band 12q24.31 — in an intron of CABP1.

What each result means

C/C No copy of the version the research linked to High-sensitivity C-reactive protein levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to High-sensitivity C-reactive protein levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to High-sensitivity C-reactive protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7965649

What is rs7965649?

rs7965649 is a single position in the genome, in or near the CABP1 gene. Published research associates it with high-sensitivity c-reactive protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7965649 linked to?

On MyGeneLog this position is linked to C-Reactive Protein Levels. The research behind each link, and its sources, are set out on that condition page.

Does having rs7965649 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7965649 come from?

GWAS Catalog, Scientific reports 2025, PMID:39747571. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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High-sensitivity C-reactive protein levels (rs7965649). MyGeneLog™. https://www.mygenelog.com/variants/rs7965649

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