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Normal pressure hydrocephalus

SLCO1A2 · rs7962263

What the study found

Who was studied 1,522 Finnish ancestry cases, 451,091 Finnish ancestry controls; replicated in 173 cases, 419,453 controls.

The effect Each copy of the T allele shifted the measure 0.308 lower (95% confidence interval 0.23-0.39); p = 9 × 10−14.

How common The T allele had a frequency of about 25% in the people studied.

Where it sits Chromosome 12, band 12p12.1 — in an intron of SLCO1A2.

What each result means

C/C No copy of the version the research linked to Normal pressure hydrocephalus. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Normal pressure hydrocephalus. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Normal pressure hydrocephalus. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7962263

What is rs7962263?

rs7962263 is a single position in the genome, in or near the SLCO1A2 gene. Published research associates it with normal pressure hydrocephalus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7962263 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7962263 come from?

GWAS Catalog, Neurology 2024, PMID:39141892. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Normal pressure hydrocephalus (rs7962263). MyGeneLog™. https://www.mygenelog.com/variants/rs7962263

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