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Smoking cessation

ANKS1B · rs7960340

What the study found

Who was studied 1,400,535 European ancestry, East Asian ancestry, Hispanic or Latin American, African ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0117 higher (95% confidence interval 0.0082-0.0152); p = 1 × 10−10.

How common The A allele had a frequency of about 14% in the people studied.

Where it sits Chromosome 12, band 12q23.1 — in an intron of ANKS1B.

What each result means

A/A Two copies of the version the research linked to Smoking cessation. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Smoking cessation. That is a smaller link than two copies.
G/G No copy of the version the research linked to Smoking cessation. This is the starting point the study compared everyone against.
Source

Questions about rs7960340

What is rs7960340?

rs7960340 is a single position in the genome, in or near the ANKS1B gene. Published research associates it with smoking cessation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7960340 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7960340 come from?

GWAS Catalog, Nature 2022, PMID:36477530. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Smoking cessation (rs7960340). MyGeneLog™. https://www.mygenelog.com/variants/rs7960340

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