KLHL42 · rs7960190
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 51,802 African American or Afro-Caribbean cases, 63,903 African American or Afro-Caribbean controls, 22,361 Hispanic or Latin American cases, 35,203 Hispanic or Latin American controls, 2,276 East Asian ancestry cases, 4,318 East Asian ancestry controls, 154,958 European ancestry cases, 276,347 European ancestry controls.
The effect Each copy of the T allele shifted the measure 0.061 higher (95% confidence interval 0.047-0.075); p = 2 × 10−20.
How common The T allele had a frequency of about 83% in the people studied.
Where it sits Chromosome 12, band 12p11.22 — in an intron of KLHL42.
rs7960190 is a single position in the genome, in or near the KLHL42 gene. Published research associates it with diabetes mellitus (phecode 250). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Diabetes mellitus (PheCode 250) (rs7960190). MyGeneLog™. https://www.mygenelog.com/variants/rs7960190