Standard

Waist circumference adjusted for body mass index

SSPN · rs7955904

Where this position leads

Condition: Waist Circumference

rs7955904 Condition: Waist Circumference Waist Circumference Condition rs7955904 rs7955904 SSPN

What the study found

Who was studied 219,872 British ancestry women.

The effect Each copy of the T allele shifted the measure 0.0344 lower (95% confidence interval 0.024-0.045); p = 3 × 10−10.

Where it sits Chromosome 12, band 12p12.1 — in an intron of SSPN-AS1.

What each result means

G/G Published research associates this genotype with typical/baseline likelihood of Waist circumference adjusted for body mass index — no copies of the reported risk allele.
G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Waist circumference adjusted for body mass index.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Waist circumference adjusted for body mass index compared to the general population.
Source

Questions about rs7955904

What is rs7955904?

rs7955904 is a single position in the genome, in or near the SSPN gene. Published research associates it with waist circumference adjusted for body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7955904 linked to?

On MyGeneLog this position is linked to Waist Circumference. The research behind each link, and its sources, are set out on that condition page.

Does having rs7955904 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7955904 come from?

GWAS Catalog, Scientific reports 2021, PMID:34021172. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Waist circumference adjusted for body mass index (rs7955904). MyGeneLog™. https://www.mygenelog.com/variants/rs7955904

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