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Seroconversion induced by one dose of COVID-19 vaccine

PLA2R1 · rs79510369

What the study found

Who was studied 15,046 European ancestry cases, 38,161 European ancestry controls.

The effect Each copy of the T allele carried 1.48 times the odds of Seroconversion induced by one dose of COVID-19 vaccine (95% confidence interval 1.36-1.6); p = 5 × 10−10.

How common The T allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 2, band 2q24.2 — in an intron of PLA2R1.

What each result means

A/A No copy of the version the research linked to Seroconversion induced by one dose of COVID-19 vaccine. This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Seroconversion induced by one dose of COVID-19 vaccine. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Seroconversion induced by one dose of COVID-19 vaccine. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs79510369

What is rs79510369?

rs79510369 is a single position in the genome, in or near the PLA2R1 gene. Published research associates it with seroconversion induced by one dose of covid-19 vaccine. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs79510369 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs79510369 come from?

GWAS Catalog, Nature communications 2024, PMID:39384777. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Seroconversion induced by one dose of COVID-19 vaccine (rs79510369). MyGeneLog™. https://www.mygenelog.com/variants/rs79510369

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