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Psoriasis

near MIR588 · rs79489735

Where this position leads

Condition: Psoriasis

rs79489735 Condition: Psoriasis Psoriasis Condition rs79489735 rs79489735 near MIR588

What the study found

Who was studied 394,626 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.357 lower (95% confidence interval 0.2-0.51); p = 4 × 10−12.

How common The C allele had a frequency of about 2% in the people studied.

Where it sits Chromosome 6, band 6q22.32 — between genes, 44.6 kb from MIR588.

What each result means

C/C Two copies of the version the research linked to Psoriasis. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Psoriasis. That is a smaller link than two copies.
T/T No copy of the version the research linked to Psoriasis. This is the starting point the study compared everyone against.
Source
A scalable variational inference approach for increased mixed-model association power
Loya H, Kalantzis G, Cooper F, Palamara PF
Nature genetics · 2025 · PMID 39789286 · open access

Questions about rs79489735

What is rs79489735?

rs79489735 is a single position in the genome, in or near the near MIR588 gene. Published research associates it with psoriasis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs79489735 linked to?

On MyGeneLog this position is linked to Psoriasis. The research behind each link, and its sources, are set out on that condition page.

Does having rs79489735 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs79489735 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Psoriasis (rs79489735). MyGeneLog™. https://www.mygenelog.com/variants/rs79489735

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