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Total testosterone levels

HSD17B2 · rs79488654

What the study found

Who was studied 194,453 European ancestry men.

The effect Each copy of the G allele shifted the measure 0.235 higher (95% confidence interval 0.15-0.32); p = 8 × 10−9.

How common The G allele had a frequency of about 100% in the people studied.

Where it sits Chromosome 16, band 16q23.3 — a missense change in HSD17B2-AS1.

What each result means

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Total testosterone levels compared to the general population.
G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Total testosterone levels.
T/T Published research associates this genotype with typical/baseline likelihood of Total testosterone levels — no copies of the reported risk allele.
Source

Questions about rs79488654

What is rs79488654?

rs79488654 is a single position in the genome, in or near the HSD17B2 gene. Published research associates it with total testosterone levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs79488654 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs79488654 come from?

GWAS Catalog, Nature medicine 2020, PMID:32042192. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Total testosterone levels (rs79488654). MyGeneLog™. https://www.mygenelog.com/variants/rs79488654

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