Who was studied 2,434 European ancestry individuals, 2,470 African American individuals, 2,065 Hispanic individuals, 702 Chinese ancestry individuals; replicated in 3,013 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.615 higher (95% confidence interval 0.42-0.81); p = 3 × 10−10.
How common The C allele had a frequency of about 5% in the people studied.
Where it sits Chromosome 10, band 10p15.2 — in an intron of PFKP.
What each result means
C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Subclinical trait of interstitial lung disease (percentage of high attenuation areas on CT scan) compared to the general population.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Subclinical trait of interstitial lung disease (percentage of high attenuation areas on CT scan).
T/TPublished research associates this genotype with typical/baseline likelihood of Subclinical trait of interstitial lung disease (percentage of high attenuation areas on CT scan) — no copies of the reported risk allele.
Respiratory research · 2017 · PMID 28521775 · open access
Questions about rs79441543
What is rs79441543?
rs79441543 is a single position in the genome, in or near the PFKP gene. Published research associates it with subclinical trait of interstitial lung disease (percentage of high attenuation areas on ct scan). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs79441543 linked to?
On MyGeneLog this position is linked to Interstitial Lung Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs79441543 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs79441543 come from?
GWAS Catalog, Respir Res 2017, PMID:28521775. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.