0 2522612318Reads by AI crawlersClaude0ChatGPT2Google · Gemini0Perplexity2Meta AI6Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others8Total25Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
The effect
Each copy of the A allele shifted the measure 0.485 lower (95% confidence interval 0.38-0.59); p = 4 × 10−19.
Where it sits Chromosome 11, band 11q12.2 — in an intron of TMEM258.
What ClinVar records
ClassificationBenign for Cholangiocarcinoma; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 3 submitters), last evaluated 2021-05-13.
ClinVar record 1174371NM_001127392.3(MYRF):c.2247+26G>A
What this is ClinVar's aggregate record for this position (as of its 2026-10-12 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
A/ATwo copies of the version the research linked to Serum metabolite ratios in chronic kidney disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Serum metabolite ratios in chronic kidney disease. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Serum metabolite ratios in chronic kidney disease. This is the starting point the study compared everyone against.
Journal of the American Society of Nephrology : JASN · 2018 · PMID 29545352
Questions about rs7943728
What is rs7943728?
rs7943728 is a single position in the genome, in or near the MYRF gene. Published research associates it with serum metabolite ratios in chronic kidney disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7943728 linked to?
On MyGeneLog this position is linked to Serum Metabolites in Chronic Kidney Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs7943728 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7943728 come from?
GWAS Catalog, J Am Soc Nephrol 2018, PMID:29545352. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 2522612318Reads by AI crawlersClaude0ChatGPT2Google · Gemini0Perplexity2Meta AI6Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others8Total25Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Serum metabolite ratios in chronic kidney disease (rs7943728). MyGeneLog™. https://www.mygenelog.com/variants/rs7943728