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Thyroid stimulating hormone levels

PRDM11 · rs7940871

What the study found

Who was studied 164,818 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.07 higher (95% confidence interval 0.062-0.078); p = 3 × 10−58.

Where it sits Chromosome 11, band 11p11.2 — in an intron of PRDM11.

What each result means

C/C Two copies of the version the research linked to Thyroid stimulating hormone levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Thyroid stimulating hormone levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Thyroid stimulating hormone levels. This is the starting point the study compared everyone against.
Source

Questions about rs7940871

What is rs7940871?

rs7940871 is a single position in the genome, in or near the PRDM11 gene. Published research associates it with thyroid stimulating hormone levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7940871 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7940871 come from?

GWAS Catalog, European journal of endocrinology 2024, PMID:39067062. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Thyroid stimulating hormone levels (rs7940871). MyGeneLog™. https://www.mygenelog.com/variants/rs7940871

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