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Mean platelet volume during first trimester of pregnancy

FBXO34 · rs79380532

What the study found

Who was studied 71,605 Chinese ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.22 higher (95% confidence interval 0.19-0.25); p = 6 × 10−47.

How common The A allele had a frequency of about 10% in the people studied.

Where it sits Chromosome 14, band 14q22.3 — in a regulatory region of FBXO34.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Mean platelet volume during first trimester of pregnancy compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Mean platelet volume during first trimester of pregnancy.
G/G Published research associates this genotype with typical/baseline likelihood of Mean platelet volume during first trimester of pregnancy — no copies of the reported risk allele.
Source

Questions about rs79380532

What is rs79380532?

rs79380532 is a single position in the genome, in or near the FBXO34 gene. Published research associates it with mean platelet volume during first trimester of pregnancy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs79380532 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs79380532 come from?

GWAS Catalog, Blood 2024, PMID:38064665. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Mean platelet volume during first trimester of pregnancy (rs79380532). MyGeneLog™. https://www.mygenelog.com/variants/rs79380532

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