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Inguinal hernia

WT1 · rs7936152

Where this position leads

Condition: Inguinal Hernia

rs7936152 Condition: Inguinal Hernia Inguinal Hernia Condition rs7936152 rs7936152 WT1

What the study found

Who was studied 13,047 European ancestry cases, 262,499 European ancestry controls; replicated in 4,450 European ancestry cases, 87,398 European ancestry controls.

The effect The reported allele is G; the catalogue records no effect size ; p = 1 × 10−11.

How common The G allele had a frequency of about 78% in the people studied.

Where it sits Chromosome 11, band 11p13 — in an intron of WT1.

What each result means

A/A No copy of the version the research linked to Inguinal hernia. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Inguinal hernia. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Inguinal hernia. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7936152

What is rs7936152?

rs7936152 is a single position in the genome, in or near the WT1 gene. Published research associates it with inguinal hernia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7936152 linked to?

On MyGeneLog this position is linked to Inguinal Hernia. The research behind each link, and its sources, are set out on that condition page.

Does having rs7936152 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7936152 come from?

GWAS Catalog, Hernia : the journal of hernias and abdominal wall surgery 2022, PMID:34382107. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Inguinal hernia (rs7936152). MyGeneLog™. https://www.mygenelog.com/variants/rs7936152

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