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Factor VII activity

MS4A6A · rs7935829

What the study found

Who was studied 20,014 European ancestry individuals, 3,420 African American individuals.

The effect Each copy of the G allele shifted the measure 0.018 higher (95% confidence interval 0.014-0.022); p = 6 × 10−18.

How common The G allele had a frequency of about 39% in the people studied.

Where it sits Chromosome 11, band 11q12.2 — in an intron of MS4A6A.

What each result means

A/A No copy of the version the research linked to Factor VII activity. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Factor VII activity. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Factor VII activity. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7935829

What is rs7935829?

rs7935829 is a single position in the genome, in or near the MS4A6A gene. Published research associates it with factor vii activity. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7935829 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7935829 come from?

GWAS Catalog, Blood 2019, PMID:30642921. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Factor VII activity (rs7935829). MyGeneLog™. https://www.mygenelog.com/variants/rs7935829

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