Sensitive

Gestational diabetes

CRY2 · rs7933420

Where this position leads

Condition: Gestational Diabetes Mellitus

rs7933420 Condition: Gestational Diabetes Mellitus Gestational Diabetes Mellitus Condition rs7933420 rs7933420 CRY2

What the study found

Who was studied 29,640 European ancestry female cases, 736,610 European ancestry female controls, 3,921 South Asian ancestry female cases, 14,233 South Asian ancestry female controls, 4,346 East Asian ancestry female cases, 23,286 East Asian ancestry female controls, 244 Hispanic or Latin American female cases, 744 Hispanic or Latin American female controls, 154 African American or Afro-Caribbean female cases, 1,272 African American or Afro-Caribbean female controls.

The effect The reported allele is T; the catalogue records no effect size ; p = 3 × 10−9.

How common The T allele had a frequency of about 53% in the people studied.

Where it sits Chromosome 11, band 11p11.2 — in an intron of CRY2.

What each result means

A/A No copy of the version the research linked to Gestational diabetes. This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Gestational diabetes. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Gestational diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7933420

What is rs7933420?

rs7933420 is a single position in the genome, in or near the CRY2 gene. Published research associates it with gestational diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7933420 linked to?

On MyGeneLog this position is linked to Gestational Diabetes Mellitus. The research behind each link, and its sources, are set out on that condition page.

Does having rs7933420 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7933420 come from?

GWAS Catalog, Nature communications 2026, PMID:42225636. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Gestational diabetes (rs7933420). MyGeneLog™. https://www.mygenelog.com/variants/rs7933420

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