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Bone mineral density (hip)

ARHGAP1 · rs7932354

What the study found

Who was studied 19,195 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.07 s.d. higher (95% confidence interval 0.05-0.09); p = 4 × 10−9.

How common The T allele had a frequency of about 29% in the people studied.

Where it sits Chromosome 11, band 11p11.2 — inside ARHGAP1.

What ClinVar records

Classification Benign; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 2 submitters), last evaluated 2021-05-16. ClinVar record 1276936 NC_000011.10:g.46700671T>C

What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.

What each result means

C/C No copy of the version the research linked to Bone mineral density (hip). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Bone mineral density (hip). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Bone mineral density (hip). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7932354

What is rs7932354?

rs7932354 is a single position in the genome, in or near the ARHGAP1 gene. Published research associates it with bone mineral density (hip). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7932354 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7932354 come from?

GWAS Catalog, Nat Genet 2009, PMID:19801982. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Bone mineral density (hip) (rs7932354). MyGeneLog™. https://www.mygenelog.com/variants/rs7932354

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