Standard

Systolic blood pressure

near BBOX1-AS1 · rs7928251

Where this position leads

Condition: Blood Pressure

rs7928251 Condition: Blood Pressure Blood Pressure Condition rs7928251 rs7928251 near BBOX1-A…

What the study found

Who was studied 507,850 East Asian ancestry individuals, 420,829 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0132 lower (95% confidence interval 0.0089-0.0175); p = 4 × 10−9.

Where it sits Chromosome 11, band 11p14.1 — between genes, 15.4 kb from BBOX1-AS1.

What each result means

G/G No copy of the version the research linked to Systolic blood pressure. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Systolic blood pressure. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Systolic blood pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7928251

What is rs7928251?

rs7928251 is a single position in the genome, in or near the near BBOX1-AS1 gene. Published research associates it with systolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7928251 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs7928251 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7928251 come from?

GWAS Catalog, Nature communications 2025, PMID:40436827. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Systolic blood pressure (rs7928251). MyGeneLog™. https://www.mygenelog.com/variants/rs7928251

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