Sensitive

Mean platelet thrombocyte volume (UKB data field 30100)

CPLX3 · rs79269642

Where this position leads

Condition: Celiac Disease

rs79269642 Condition: Celiac Disease Celiac Disease Condition rs79269642 rs79269642 CPLX3

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0194 higher (95% confidence interval 0.014-0.025); p = 4 × 10−12.

How common The C allele had a frequency of about 9% in the people studied.

Where it sits Chromosome 15, band 15q24.1 — in the 3′ untranslated region of CPLX3.

What each result means

C/C Two copies of the version the research linked to Mean platelet thrombocyte volume (UKB data field 30100). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Mean platelet thrombocyte volume (UKB data field 30100). That is a smaller link than two copies.
T/T No copy of the version the research linked to Mean platelet thrombocyte volume (UKB data field 30100). This is the starting point the study compared everyone against.
Source

Questions about rs79269642

What is rs79269642?

rs79269642 is a single position in the genome, in or near the CPLX3 gene. Published research associates it with mean platelet thrombocyte volume (ukb data field 30100). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs79269642 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs79269642 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs79269642 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Mean platelet thrombocyte volume (UKB data field 30100) (rs79269642). MyGeneLog™. https://www.mygenelog.com/variants/rs79269642

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