C/CPublished research associates this genotype with typical/baseline likelihood of Mosaic loss of chromosome Y (Y chromosome dosage) — no copies of the reported risk allele.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Mosaic loss of chromosome Y (Y chromosome dosage).
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Mosaic loss of chromosome Y (Y chromosome dosage) compared to the general population.
Nature communications · 2019 · PMID 31624269 · open access
Questions about rs79058858
What is rs79058858?
rs79058858 is a single position in the genome, in or near the FLT3LG gene. Published research associates it with mosaic loss of chromosome y (y chromosome dosage). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs79058858 linked to?
On MyGeneLog this position is linked to Mosaic Loss of Chromosome Y. The research behind each link, and its sources, are set out on that condition page.
Does having rs79058858 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs79058858 come from?
GWAS Catalog, Nat Commun 2019, PMID:31624269. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.