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Bone properties (heel)

MBL2 · rs7902708

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 2,483 East Asian ancestry individuals, 1,885 European ancestry individuals, 11,146 individuals; replicated in 10,074 European ancestry individuals, 2,870 European and other ancestry individuals, 21,434 individuals.

The effect Each copy of the G allele shifted the measure 0.09 higher (95% confidence interval 0.07-0.12); p = 5 × 10⁻¹⁵.

How common The G allele had a frequency of about 88% in the people studied.

Where it sits Chromosome 10, band 10q21.1 — in an intron of LNCAROD.

What each result means

C/C No copy of the version the research linked to Bone properties (heel). This is the starting point the study compared everyone against.

C/G One copy of the version the research linked to Bone properties (heel). That is a smaller link than two copies.

G/G Two copies of the version the research linked to Bone properties (heel). That is the strongest link of the three results. A link in a study is not a diagnosis.

Source

Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium

Moayyeri A, Hsu YH, Karasik D, Estrada K, Xiao SM, Nielson C, Srikanth P, Giroux S, Wilson SG, Zheng HF, Smith AV, Pye SR

and 118 more — show all

Leo PJ, Teumer A, Hwang JY, Ohlsson C, McGuigan F, Minster RL, Hayward C, Olmos JM, Lyytikäinen LP, Lewis JR, Swart KM, Masi L, Oldmeadow C, Holliday EG, Cheng S, van Schoor NM, Harvey NC, Kruk M, del Greco M F, Igl W, Trummer O, Grigoriou E, Luben R, Liu CT, Zhou Y, Oei L, Medina-Gomez C, Zmuda J, Tranah G, Brown SJ, Williams FM, Soranzo N, Jakobsdottir J, Siggeirsdottir K, Holliday KL, Hannemann A, Go MJ, Garcia M, Polasek O, Laaksonen M, Zhu K, Enneman AW, McEvoy M, Peel R, Sham PC, Jaworski M, Johansson Å, Hicks AA, Pludowski P, Scott R, Dhonukshe-Rutten RA, van der Velde N, Kähönen M, Viikari JS, Sievänen H, Raitakari OT, González-Macías J, Hernández JL, Mellström D, Ljunggren O, Cho YS, Völker U, Nauck M, Homuth G, Völzke H, Haring R, Brown MA, McCloskey E, Nicholson GC, Eastell R, Eisman JA, Jones G, Reid IR, Dennison EM, Wark J, Boonen S, Vanderschueren D, Wu FC, Aspelund T, Richards JB, Bauer D, Hofman A, Khaw KT, Dedoussis G, Obermayer-Pietsch B, Gyllensten U, Pramstaller PP, Lorenc RS, Cooper C, Kung AW, Lips P, Alen M, Attia J, Brandi ML, de Groot LC, Lehtimäki T, Riancho JA, Campbell H, Liu Y, Harris TB, Akesson K, Karlsson M, Lee JY, Wallaschofski H, Duncan EL, O'Neill TW, Gudnason V, Spector TD, Rousseau F, Orwoll E, Cummings SR, Wareham NJ, Rivadeneira F, Uitterlinden AG, Prince RL, Kiel DP, Reeve J, Kaptoge SK

Human molecular genetics · 2014 · PMID 24430505

Questions about rs7902708

What is rs7902708?

rs7902708 is a single position in the genome, in or near the MBL2 gene. Published research associates it with bone properties (heel). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7902708 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7902708 come from?

GWAS Catalog, Human molecular genetics 2014, PMID:24430505. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Bone properties (heel) (rs7902708). MyGeneLog™. https://www.mygenelog.com/variants/rs7902708

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