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Liver enzyme levels (alkaline phosphatase)

LINC02667 · rs7901425

What the study found

Who was studied 437,438 European ancestry individuals; replicated in 315,572 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.00196 higher (95% confidence interval 0.0014-0.0025); p = 7 × 10−13.

How common The T allele had a frequency of about 77% in the people studied.

Where it sits Chromosome 10, band 10q26.3 — between genes, 173.4 kb from LINC02667.

What each result means

C/C No copy of the version the research linked to Liver enzyme levels (alkaline phosphatase). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Liver enzyme levels (alkaline phosphatase). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Liver enzyme levels (alkaline phosphatase). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7901425

What is rs7901425?

rs7901425 is a single position in the genome, in or near the LINC02667 gene. Published research associates it with liver enzyme levels (alkaline phosphatase). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7901425 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7901425 come from?

GWAS Catalog, Nature communications 2021, PMID:33972514. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Liver enzyme levels (alkaline phosphatase) (rs7901425). MyGeneLog™. https://www.mygenelog.com/variants/rs7901425

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