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Coronary artery calcium score

near ZNF536 · rs78857392

What the study found

Who was studied 2,693 Korean ancestry individuals.

The effect Each copy of the C allele shifted the measure 222 lower; p = 2 × 10−12.

How common The C allele had a frequency of about 2% in the people studied.

Where it sits Chromosome 19, band 19q12 — between genes, 84.9 kb from ZNF536.

What each result means

C/C Two copies of the version the research linked to Coronary artery calcium score. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Coronary artery calcium score. That is a smaller link than two copies.
T/T No copy of the version the research linked to Coronary artery calcium score. This is the starting point the study compared everyone against.
Source

Questions about rs78857392

What is rs78857392?

rs78857392 is a single position in the genome, in or near the near ZNF536 gene. Published research associates it with coronary artery calcium score. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs78857392 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs78857392 come from?

GWAS Catalog, Scientific reports 2022, PMID:35121771. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Coronary artery calcium score (rs78857392). MyGeneLog™. https://www.mygenelog.com/variants/rs78857392

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