Sensitive

Response to antiepileptic mood-stabilizing treatment in bipolar disorder

THSD7A · rs78835388

Where this position leads

Condition: Bipolar Disorder

rs78835388 Condition: Bipolar Disorder Bipolar Disorder Condition rs78835388 rs78835388 THSD7A

What the study found

Who was studied 199 European ancestry cases.

The effect Each copy of the G allele shifted the measure 6.6 lower; p = 7 × 10−9.

How common The G allele had a frequency of about 2% in the people studied.

Where it sits Chromosome 7, band 7p21.3 — in an intron of THSD7A.

What each result means

A/A No copy of the version the research linked to Response to antiepileptic mood-stabilizing treatment in bipolar disorder. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Response to antiepileptic mood-stabilizing treatment in bipolar disorder. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Response to antiepileptic mood-stabilizing treatment in bipolar disorder. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs78835388

What is rs78835388?

rs78835388 is a single position in the genome, in or near the THSD7A gene. Published research associates it with response to antiepileptic mood-stabilizing treatment in bipolar disorder. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs78835388 linked to?

On MyGeneLog this position is linked to Bipolar Disorder. The research behind each link, and its sources, are set out on that condition page.

Does having rs78835388 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs78835388 come from?

GWAS Catalog, Clinical pharmacology and therapeutics 2020, PMID:32627186. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Response to antiepileptic mood-stabilizing treatment in bipolar disorder (rs78835388). MyGeneLog™. https://www.mygenelog.com/variants/rs78835388

← See all variants