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Cholesterol to Total Lipids in Medium LDL percentage

near LPL · rs78810414

Where this position leads

Condition: Cholesterol (LDL, HDL and Total)

rs78810414 Condition: Cholesterol (LDL, HDL and Total) Cholesterol (LDL, HDL and Total) Condition rs78810414 rs78810414 near LPL

What the study found

Who was studied 203,300 British ancestry males.

The effect Each copy of the T allele shifted the measure 0.0861 % higher (95% confidence interval 0.076-0.096); p = 8 × 10−64.

Where it sits Chromosome 8, band 8p21.3 — between genes, 46.3 kb from LPL.

What each result means

C/C No copy of the version the research linked to Cholesterol to Total Lipids in Medium LDL percentage. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Cholesterol to Total Lipids in Medium LDL percentage. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Cholesterol to Total Lipids in Medium LDL percentage. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs78810414

What is rs78810414?

rs78810414 is a single position in the genome, in or near the near LPL gene. Published research associates it with cholesterol to total lipids in medium ldl percentage. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs78810414 linked to?

On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.

Does having rs78810414 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs78810414 come from?

GWAS Catalog, Nature genetics 2025, PMID:41044249. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Cholesterol to Total Lipids in Medium LDL percentage (rs78810414). MyGeneLog™. https://www.mygenelog.com/variants/rs78810414

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