C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Lung disease severity in cystic fibrosis compared to the general population.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Lung disease severity in cystic fibrosis.
T/TPublished research associates this genotype with typical/baseline likelihood of Lung disease severity in cystic fibrosis — no copies of the reported risk allele.
Nature communications · 2015 · PMID 26417704 · open access
Questions about rs7879546
What is rs7879546?
rs7879546 is a single position in the genome, in or near the AGTR2 gene. Published research associates it with lung disease severity in cystic fibrosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7879546 linked to?
On MyGeneLog this position is linked to Cystic Fibrosis. The research behind each link, and its sources, are set out on that condition page.
Does having rs7879546 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7879546 come from?
GWAS Catalog, Nat Commun 2015, PMID:26417704. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.