Cognitive decline rate in late mild cognitive impairment
EIF4G3 · rs78649275
0 2932122222112Reads by AI crawlersClaude3ChatGPT2Google · Gemini1Perplexity2Meta AI2Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others12Total29Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 472 European ancestry cases, 47 cases.
The effect
Each copy of the T allele shifted the measure 0.595 higher (95% confidence interval 0.39-0.8); p = 4 × 10−8.
How common The T allele had a frequency of about 1% in the people studied.
Where it sits Chromosome 1, band 1p36.12 — in an intron of EIF4G3.
What each result means
C/CNo copy of the version the research linked to Cognitive decline rate in late mild cognitive impairment. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Cognitive decline rate in late mild cognitive impairment. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Cognitive decline rate in late mild cognitive impairment. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs78649275 is a single position in the genome, in or near the EIF4G3 gene. Published research associates it with cognitive decline rate in late mild cognitive impairment. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs78649275 linked to?
On MyGeneLog this position is linked to Cognitive Decline Rate in Late MCI. The research behind each link, and its sources, are set out on that condition page.
Does having rs78649275 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs78649275 come from?
GWAS Catalog, PLoS One 2015, PMID:26252872. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 2932122222112Reads by AI crawlersClaude3ChatGPT2Google · Gemini1Perplexity2Meta AI2Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others12Total29Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Cognitive decline rate in late mild cognitive impairment (rs78649275). MyGeneLog™. https://www.mygenelog.com/variants/rs78649275