1 4722128223223Reads by AI crawlersClaude2ChatGPT2Google · Gemini1Perplexity2Meta AI8Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others23Total47Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied up to 14,459 European ancestry females, up to 10,936 European ancestry males, up to 433 Old Order Amish females, up to 592 Old Order Amish males.
The effect
Each copy of the A allele shifted the measure 0.108 higher (95% confidence interval 0.071-0.145); p = 2 × 10−8.
How common The A allele had a frequency of about 53% in the people studied.
Where it sits Chromosome 9, band 9q34.3 — in an intron of LHX3.
What ClinVar records
ClassificationBenign for Non-acquired combined pituitary hormone deficiency with spine abnormalities; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 3 submitters), last evaluated 2021-07-10.
ClinVar record 1185281NM_178138.6(LHX3):c.776-90C>T
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
A/ATwo copies of the version the research linked to Thyroid hormone levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Thyroid hormone levels. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Thyroid hormone levels. This is the starting point the study compared everyone against.
PLoS genetics · 2013 · PMID 23408906 · open access
Questions about rs7860634
What is rs7860634?
rs7860634 is a single position in the genome, in or near the LHX3 gene. Published research associates it with thyroid hormone levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7860634 linked to?
On MyGeneLog this position is linked to Thyroid Stimulating Hormone (TSH) Levels. The research behind each link, and its sources, are set out on that condition page.
Does having rs7860634 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7860634 come from?
GWAS Catalog, PLoS Genet 2013, PMID:23408906. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 4722128223223Reads by AI crawlersClaude2ChatGPT2Google · Gemini1Perplexity2Meta AI8Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others23Total47Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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