CAVIN2-AS1 · rs78598566
Where this position leads
Condition: QT Interval and Drug-Induced Long QT
What the study found
Who was studied 86,165 European ancestry individuals, 13,975 Hispanic or Latin American individuals, 5,034 East Asian ancestry individuals, 8,457 African American individuals, 310 South Asian ancestry individuals, 1,631 Asian ancestry individuals, 1,370 Native Hawaiian ancestry individuals, 226 Native American ancestry individuals, 364 individuals.
The effect Each copy of the C allele shifted the measure 0.87 higher; p = 3 × 10−10.
How common The C allele had a frequency of about 10% in the people studied.
Where it sits Chromosome 2, band 2q32.3 — in an intron of CAVIN2-AS1.
rs78598566 is a single position in the genome, in or near the CAVIN2-AS1 gene. Published research associates it with qt interval. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to QT Interval and Drug-Induced Long QT. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Genetics 2022, PMID:36271874. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
QT interval (rs78598566). MyGeneLog™. https://www.mygenelog.com/variants/rs78598566